Eazy-E quickly released his vanguard solo LP, Eazy-Duz-It, which went double-platinum. Ice Cube left N.W.A. in 1989 due to personality conflicts, and Eazy-E largely took over Cube's writing and rapping duties for Efil4zaggin (1991). The album was not as successful as Straight Outta Compton, and N.W.A. soon broke up, initiating a long court battle between the various members of N.W.A., Heller, Ruthless Records and Death Row Records (Dr. Dre's label, headed by Suge Knight). Dr. Dre's solo debut, the blockbuster hit The Chronic made fun of Eazy-E on several tracks. In response Eazy-E released a second solo album "It's on(Dr.Dre)187um Killa, " which eventually sold more than 1.5 million copies. The album contains repeated references to Dr.Dre and Snoop Doggy Dogg. The album shows Dre on the album's inner sleeve dressed in drag wearing eye shadow, lipstick and sequins. Ruthless Records found considerable success with Above the Law, MC Ren, H.W.A. and, most famously, Bone Thugs-N-Harmony. Eazy-E never managed to regain street credibility, vocally supporting Theodore Briseno, one of the police officers who took part in the Rodney King beating and attending a Republican fundraiser.
In 1995, Eazy-E entered the hospital with what he believed to be developing asthma. He was diagnosed with AIDS, and almost immediately announced his illness to the public. He died soon after, on March 26, 1995. Str8 Off tha Streetz of Muthaphukkin Compton was released posthumously, followed by some previously unreleased material under the name Impact of a Legend. He fathered nine children by seven different women.